- P-ISSN 2233-4203
- E-ISSN 2093-8950
- Apply for Authority
- P-ISSN2233-4203
- E-ISSN2093-8950
Article Detail
Home > Article Detail
UHPLC-ESI-qTOF-MS Analysis of Cyclopeptide Alkaloids in the Seeds of Ziziphus jujuba var. spinosa
Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2016, v.7 no.2, pp.45-49
https://doi.org/10.5478/MSL.2016.7.2.45
(Seoul National University)
(Kyung Hee University)
(Seoul National University)
(Seoul National University)
(Kyung Hee University)
(Seoul National University)
(Seoul National University)
Kang,
K. B., Jang,
D. S., Kim,
J., &
Sung,
S.
H.
(2016). UHPLC-ESI-qTOF-MS Analysis of Cyclopeptide Alkaloids in the Seeds of Ziziphus jujuba var. spinosa. Mass Spectrometry Letters, 7(2), 45-49, https://doi.org/10.5478/MSL.2016.7.2.45
- Downloaded
- Viewed
Abstract
An UHPLC-ESI-qTOF-MS analytical method was developed for cyclopeptide alkaloids in the seeds of Ziziphus jujuba var. spinosa (Semen Ziziphi Spinosae), which is a commonly used herb in Chinese and Korean traditional medicines. Considering the basicity of cyclopeptide alkaloids, a specific separation method was developed for an UHPLC system. The compounds were detected by DAD and ESI-qTOF-MS, and their fragmentation patterns were also acquired by MSE technologies. Peak-picking of major compounds was performed with nine previously isolated compounds and two reference standard compounds. Tandem MS fragmentation behaviors of type-Ia and -Ib cyclopeptide alkaloids were investigated with the acquired data to develop a strategy for dereplication of other cyclopeptide alkaloid compounds in Z. jujuba var. spinosa. Two more cyclopeptide alkaloids were tentatively identified with UHPLC–ESI-qTOF-MS using this method.
- keywords
- Cyclopeptide alkaloids, UHPLC–ESI-qTOF-MS, Ziziphus jujuba var. spinosa
Reference
1
Tan, N. H.. (2006). . Chem. Rev, 106, 840-.
2
Gournelis, D. C.. (1998). Progress in the Chemistry of Organic Natural Products, Vol. 75:Springer-Verlag.
3
Schmidt, U.. (1985). The Alkaloids - Chemistry and Pharmacology. Vol. 26:Academic Press.
4
Park, J. H.. (2004). . J. Ethnopharmacol, 95, 39-.
5
Jiang, J. G.. (2007). . Nat. Prod. Res, 21, 310-.
6
Cao, J. X.. (2010). . J. Ethnopharmacol, 130, 163-.
7
Ma, Y.. (2008). . J. Ethnopharmacol, 117, 318-.
8
Han, H.. (2009). . Pharmacol. Biochem. Behav, 92, 206-.
9
Rosekind, M. R.. (2010). . Am. J. Manag. Care, 16(8), 617-.
10
Francois, C.. (2010). . J. Med. Econ, 13, 99-.
11
Kang, K. B.. (2015). . Phytochemistry, 119, 90-.
12
Wolfender, J. L.. (2015). . J. Chromatogr. A, 1382, 136-.
13
Aldini, G.. (2011). . J. Chromatogr. A, 1218, 2856-.
14
Plumb, R. S.. (2006). . Rapid Commun. Mass Spectrom, 20, 1989-.
15
Trevisan, G.. (2009). . J. Nat. Prod, 72, 608-.
16
김원일. (2014). Quantitative and pattern recognition analyses of magnoflorine, spinosin, 6000-feruloyl spinosin and jujuboside A by HPLC in Zizyphi Semen. Archives of Pharmacal Research, 37(9), 1139-1147.
17
Otsuka, H.. (1974). . Phytochemistry, 13, 2016-.
18
Paizs, B.. (2005). . Mass Spectrom. Rev, 24, 508-.
19
Shah, A. H.. (1989). . Pakistan J. Pharm. Sci, 2, 81-.
- Submission Date
- 2016-05-11
- Revised Date
- 2016-06-20
- Accepted Date
- 2016-06-21
Other articles from this issue
- Recent Developments in Nuclear Forensic and Nuclear Safeguards Analysis Using Mass Spectrometry
- Uranium Particle Identification with SEM-EDX for Isotopic Analysis by Secondary Ion Mass Spectrometry
- UHPLC-ESI-qTOF-MS Analysis of Cyclopeptide Alkaloids in the Seeds of Ziziphus jujuba var. spinosa
- Improvement of Measurement Precisions for Uranium Isotopes at Ultra Trace Levels by Modification of the Sample Introduction System in MC-ICP-MS
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.