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- E-ISSN 2093-8950
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Simulation Study to Improve Ion Transmission Efficiency in Mass Spectrometry with a Dual Ion Funnel Ion Source
Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2013, v.4 no.4, pp.91-94
https://doi.org/10.5478/MSL.2013.4.4.91
(Korea Basic Science Institute)
(Korea Basic Science Institute)
(Bioneer Corporation)
(Korea Basic Science Institute)
(Korea Basic Science Institute)
(Bioneer Corporation)
(Korea Basic Science Institute)
Baek,
S. J., Kim,
S. Y., Kim,
T., &
Kim,
H.
S.
(2013). Simulation Study to Improve Ion Transmission Efficiency in Mass Spectrometry with a Dual Ion Funnel Ion Source. Mass Spectrometry Letters, 4(4), 91-94, https://doi.org/10.5478/MSL.2013.4.4.91
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Abstract
We performed computer simulations to improve transmission efficiencies of a dual ion funnel system implemented onan FT-ICR MS. We found that the low m/z range from 50 to 150 could be significantly improved by operating the two ion funnelsat different RF amplitudes. These new operational conditions could be applied to analyze metabolome samples, whichrequire high sensitivity in the m/z range from 50 to 1,000.
- keywords
- FT-ICR, ion funnel, trajectory calculation, simulations, SIMION
Reference
1
Shaffer, S. A. (1997). . Rapid Communications in Mass Spectrometry, 11, 1813-.
2
Kim, T. (2000). . Anal. Chem, 72, 2247-.
3
Kim, T. “Ion guide for mass spectrometers”, US Patent 7,495,212.
4
Cobb, J. S. (2010). . J. Am. Soc. Mass Spectrom, 21(6), 949-.
5
Dahl, D. A.. SIMION 3D (Version 8.1) Idaho National Engineering and Environmental Laboratory; Idaho Falls, ID, 2000.
6
Tolmachev, A. V. (2000). . Int. J. Mass Spectrom, 203, 31-.
7
Kim, T. (1997). .
- Submission Date
- 2013-12-17
- Revised Date
- 2013-12-24
- Accepted Date
- 2013-12-24
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