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- E-ISSN 2093-8950
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- P-ISSN2233-4203
- E-ISSN2093-8950
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Gas Chromatography-High Resolution Tandem Mass Spectrometry Using a GC-APPI-LIT Orbitrap for Complex Volatile Compounds Analysis
Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2012, v.3 no.2, pp.29-38
https://doi.org/10.5478/MSL.2012.3.2.29
(Iowa State University, Ames Laboratory)
(Iowa State University, Ames Laboratory)
(Iowa State University, Ames Laboratory)
(Iowa State University, Ames Laboratory)
(Iowa State University, Ames Laboratory)
Lee,
Y. J., Smith,
E. A., &
Jun,
J.
H.
(2012). Gas Chromatography-High Resolution Tandem Mass Spectrometry Using a GC-APPI-LIT Orbitrap for Complex Volatile Compounds Analysis. Mass Spectrometry Letters, 3(2), 29-38, https://doi.org/10.5478/MSL.2012.3.2.29
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Abstract
A new approach of volatile compounds analysis is proposed using a linear ion trap Orbitrap mass spectrometer coupledwith gas chromatography through an atmospheric pressure photoionization interface. In the proposed GC-HRMS/MSapproach, direct chemical composition analysis is made for the precursor ions in high resolution MS spectra and the structuralidentifications were made through the database search of high quality MS/MS spectra. Successful analysis of a complex perfumesample was demonstrated and compared with GC-EI-Q and GC-EI-TOF. The current approach is complementary to conventionalGC-EI-MS analysis and can identify low abundance co-eluting compounds. Toluene co-sprayed as a dopant through APIprobe significantly enhanced ionization of certain compounds and reduced oxidation during the ionization.
- keywords
- Gas chromatography, Atmospheric pressure photoionization (APPI), Linear ion trap (LIT), Orbitrap, Volatile compounds
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- Submission Date
- 2012-06-08
- Revised Date
- 2012-06-17
- Accepted Date
- 2012-06-17
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